By Lijie Grace Zhang, John P Fisher, Kam Leong
3D Bioprinting and Nanotechnology in Tissue Engineering presents a detailed advent to those applied sciences and their commercial functions. Stem cells in tissue regeneration are lined, besides nanobiomaterials. Commercialization, felony and regulatory issues also are mentioned with the intention to assist you translate nanotechnology and 3D printing-based items to and the hospital. Dr. Zhang’s and Dr. Fishers’ crew of specialist members have pooled their services so one can supply a precis of the suitability, sustainability and obstacles of every strategy for every particular software. The expanding availability and lowering expenditures of nanotechnologies and 3D printing applied sciences are using their use to satisfy scientific wishes, and this publication presents an summary of those applied sciences and their integration. It indicates how nanotechnology can raise the medical potency of prosthesis or synthetic tissues made via bioprinting or biofabrication. scholars and execs will obtain a balanced evaluation of appropriate know-how with theoretical origin, whereas nonetheless studying in regards to the latest printing techniques.
- Includes medical functions, regulatory hurdles, and risk-benefit research of every technology.
- This booklet will help you in selecting the right fabrics and choosing the precise parameters for printing, plus comprise cells and biologically energetic brokers right into a published constitution
- Learn some great benefits of integrating 3D printing and nanotechnology to be able to increase the security of your nano-scale fabrics for biomedical applications
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Additional resources for 3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine
A and b) Top and lateral view of the branched scaffold. (c and d) Top and lateral views, respectively, of the multilumen scaffold. (e and f) Schwann cells seeded inside the scaffold. , 2011). , 2014). , 2014). g. swelling and stiffness) based on monomer percentage. 8 Complex 3D cell-encapsulated scaffolds fabricated by the DOPsL system. (a and b) Bright field micrographs of GelMA scaffolds with encapsulated NIH/3T3 cells at different time points. (c) 3D reconstruction of confocal fluorescence micrographs of cell–scaffold interaction.
Twenty layers of each cell line were stacked to mimic 3D skin structure. , 2004). Matrigel® was spin-coated on quartz 10–30 mm thickness, and the substrate had a Matrigel® layer on its cell receiving face. An ArF excimer laser was set with 193 nm wavelength and 400 mJ/cm2 laser fluence. Cell viability was over 95% for 24 h post-transfer. The comet assay was employed to evaluate DNA damage; the results showed no noticeable damage. Cell differentiation was induced via adding retinoic acid or dimethyl sulfoxide (DMSO; 1%).
2007). In contrast to the point-by-point processing by laser-based SLA, optical projection stereolithogra phy employs DMD to fabricate 3D hydrogel objects layer-by-layer using UV irradiation. Suri et al. , 2011). With an improved version of the dynamic optical projection stereolithography (DOPsL) system, Soman et al. 9 SEM images of woodpile structures fabricated from PEGDA by TPP: (a) large view, (b) close-up view (Zhang and Chen, 2011). 10 SEM images of microdot array with various feature sizes fabricated from PEGDA by TPP (Zhang and Chen, 2011).
3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine by Lijie Grace Zhang, John P Fisher, Kam Leong